组蛋白H1与吡喃共聚物的相互作用。
The interaction of histone H1 with pyran co-polymer.
作者信息
Reczek P R
出版信息
Res Commun Chem Pathol Pharmacol. 1981 Oct;34(1):105-14.
PMID:7313294
Abstract
Complexes formed by the interaction of histone H1 and the immunomodulator Pyran co-polymer, were evaluated using nephelometric titration. At a constant concentration of histone (10 microgram/ml), maximum turbidity was obtained at a Pyran concentration of 2 microgram/ml. Titration of H1 by Pyran was found to be sensitive to ionic strength. Concentration of Na+ greater than 200 mM or Mg+2 greater than 3 mM apparently blocked Pyran . H1 complex formation.
摘要
利用比浊滴定法评估了组蛋白H1与免疫调节剂吡喃共聚物相互作用形成的复合物。在组蛋白浓度恒定（10微克/毫升）的情况下，吡喃浓度为2微克/毫升时获得了最大浊度。发现吡喃对H1的滴定对离子强度敏感。Na⁺浓度大于200 mM或Mg²⁺浓度大于3 mM明显会阻止吡喃与H1形成复合物。
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