间羟叔丁肾上腺素与气管和支气管平滑肌：与治疗哮喘的各种药物的体外和体内比较研究
Reproterol and the muscle of the trachea and bronchi: in vitro and in vivo comparative studies with various drugs used in the treatment of asthma.
作者信息
Di Mezza F, Giordano L, Scognamiglio M, Montanaro A, Marmo E
出版信息
Respiration. 1981;42(3):175-83. doi: 10.1159/000194425.
PMID:7313343
Abstract
In vitro in vivo reproterol showed intense spasmolytic effects upon the trachea and bronchi against various spasm-including agents (histamine, acetylcholine, acetyl-beta-methylcholine, 5-hydroxytryptamine, BaCl2). A comparative study with various drug used in the treatment of asthma (isoprenaline, metaproterenol, salbutamol, clenbuterol, papaverine and atropine) has been conducted.
摘要
体外和体内研究表明，间羟异丙肾上腺素对气管和支气管具有强烈的解痉作用，可对抗多种致痉剂（组胺、乙酰胆碱、乙酰-β-甲基胆碱、5-羟色胺、氯化钡）。已对用于治疗哮喘的多种药物（异丙肾上腺素、间羟舒喘宁、沙丁胺醇、克仑特罗、罂粟碱和阿托品）进行了对比研究。
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