Lustenberger F X, Zingg E J
Schweiz Med Wochenschr. 1981 Dec 19;111(51):2005-11.
Between 1971 and 1981, 120 patients or 127 kidneys underwent surgery for staghorn calculi in the Department of Urology at the University of Berne. The following surgical procedures were performed: 7 primary nephrectomies, 29 intrasinusal pyelotomies by the method of Gil-Vernet, 69 nephrotomies, 17 partial resections and 5 nephrotomies combined with partial resection of the kidney. All the surgical procedure in the parenchyma were done in cold ischemia produced by regional cooling of the surface with ice. In our retrospective study special emphasis is placed on important functional aspects of the surgical technique and possible intraoperative and early postoperative complications. Secondary nephrectomy was necessary in only one case. In 102 patients it was possible to record the late results after an average observation time of 4.8 years. 75% of the patients showed good results i.e. they were free of infections and stones and the intravenous urogram was functionally satisfactory. 15.6% had residual stones or recurrent stone formation whereas only 4.9% presented with chronic urinary infections resistant to therapy despite the absence of detectable stones. In 25 patients who underwent differential 131I-hippuran clearance studies the average loss of function was 8.6% for the kidney operated on in hypothermia. In the same 10-year period there were only 7 cases with staghorn calculi (all over 55 years of age) in which primary nephrectomy was necessary because of silent hydronephrosis or pyonephrosis. Our results are compared with a series published by Blandy and Singh who followed 60 patients in whom staghorn calculi were treated exclusively by conservative means. Today new surgical techniques make it possible to free the kidney of staghorn calculi without major loss of renal function, and they remain free of calculi and infection if the metaphylaxis is carefully followed.
1971年至1981年间,伯尔尼大学泌尿外科为120例患者或127个肾脏进行了鹿角形结石手术。实施了以下手术:7例初次肾切除术、29例采用吉尔 - 韦尔内方法的窦内肾盂切开术、69例肾切开取石术、17例部分肾切除术以及5例肾切开取石术联合肾脏部分切除术。实质内的所有手术均在通过冰局部冷却表面产生的冷缺血状态下进行。在我们的回顾性研究中,特别强调了手术技术的重要功能方面以及可能的术中及术后早期并发症。仅1例需要二次肾切除术。102例患者在平均4.8年的观察期后记录了远期结果。75%的患者效果良好,即无感染和结石,静脉肾盂造影显示功能满意。15.6%有残余结石或结石复发,而仅有4.9%尽管未检测到结石但存在对治疗有抵抗的慢性尿路感染。在25例接受131I - 马尿酸盐清除差异研究的患者中,接受低温手术的肾脏功能平均丧失8.6%。在同一10年期间,仅7例鹿角形结石患者(均超过55岁)因无症状肾积水或脓肾而需要进行初次肾切除术。我们的结果与布兰迪和辛格发表的一系列研究结果进行了比较,他们随访了仅采用保守方法治疗鹿角形结石的60例患者。如今,新的手术技术使在不造成肾功能重大损失的情况下清除肾脏鹿角形结石成为可能,并且如果仔细遵循预防措施,肾脏可保持无结石和无感染状态。