红细胞膜的研究。V. 水杨酸甲酯的溶血作用及其可能机制。
Studies on erythrocyte membrane. V. Haemolytic effect of methylsalicylate and its possible mechanism.
作者信息
Murugesh N, Kumar V R, Vembar S, Damodaran C
出版信息
Toxicol Lett. 1981 Nov;9(3):225-9. doi: 10.1016/0378-4274(81)90154-5.
PMID:7314129
Abstract
The haemolytic effect of methylsalicylate (MS) on human and sheep erythrocytes is reported for the first time to our knowledge. Human erythrocytes are more sensitive to this effect. Haemolysis is proportional to the concentration of methylsalicylate and the duration of incubation. Lowering of surface tension and the ensuing membrane damage appear to be the mechanism by which the haemolytic effect is produced.
摘要
据我们所知，首次报道了水杨酸甲酯（MS）对人和绵羊红细胞的溶血作用。人红细胞对这种作用更敏感。溶血作用与水杨酸甲酯的浓度和孵育时间成正比。表面张力的降低及随之而来的膜损伤似乎是产生溶血作用的机制。
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