Pathology of childhood nephrotic syndrome in northern Nigeria.

Histopathology of kidney biopsies in 46 children with nephrotic syndrome in northern Nigeria showed that 15 had quartan malarial nephropathy, 14 membranoproliferative glomerulonephritis, six proliferative glomerulonephritis and four chronic glomerulonephritis. There were only two cases of minimal change lesion. No set of clinical features typify any particular histologic diagnosis. There was progression of glomerular lesion in five of the ten children who had repeat biopsy.