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[受血者免疫红细胞同种抗体引起的犊牛继发性免疫性输血休克的血液形态学变化]

[Morphological blood changes in calves with secondary immune blood transfusion shock caused by the recipients' immune erythrocyte isoantibodies].

作者信息

Golemanov D

出版信息

Vet Med Nauki. 1981;18(4):65-70.

PMID:7314443
Abstract

Investigations were carried out with 10 clinically normal calves, aged 1 to 6 months, through transfusion of 2-4 cm3/kg incompatible isogenic blood against which the recipients had immune isoerythrocyte antibodies of 1:2 to 1:32 titers. All animals, were studied for hemoglobin content, total erythrocyte and leukocyte count, leukocyte formula, and erythrocyte sedimentation rate (ESR) prior to the transfusion of blood and at the 1st, 4th and 24th hour and on the 4th and 7th day. An abrupt drop of hemoglobin was established at the 1st and 4th hour following hemotransfusion, while the erythrocytes dropped at the 4th hour. Within the remaining periods of time these two indices fluctuated around the normal value. Low or high ESR/1 and 2 hours showed no connection with the changes in the erythrocyte count. Lasting leukopenia was established along with transient eosinopenia, well exposed neutropenia, lymphocytosis, and monocytosis.

摘要

对10头1至6个月大的临床正常小牛进行了研究,通过输入每千克体重2 - 4立方厘米不相容的同基因血液,这些小牛针对该血液产生了滴度为1:2至1:32的免疫同种红细胞抗体。在输血前以及输血后第1、4和24小时以及第4和7天,对所有动物进行血红蛋白含量、红细胞和白细胞总数、白细胞分类以及红细胞沉降率(ESR)的研究。输血后第1和4小时血红蛋白出现突然下降,而红细胞在第4小时下降。在其余时间段内,这两个指标在正常值附近波动。ESR在1和2小时时的低或高与红细胞计数的变化没有关联。出现了持续性白细胞减少以及短暂性嗜酸性粒细胞减少、明显的中性粒细胞减少、淋巴细胞增多和单核细胞增多。

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