Hoflehner G, Golob E
Wien Med Wochenschr. 1981 Oct 15;131(19):475-7.
In a patient with gestational trophoblastic disease midtrimester abortion was induced by intravenous application of prostaglandin F2 alpha. After evacuation of the uterus the patient developed a severe acute respiratory distress syndrome (ARDS). This syndrome has been described as resulting from trophoblastic emboli, hemorrhage shock, gestational osmotic imbalance or disseminated intravascular coagulation. Also an indirect side effect of prostaglandin has to be discussed. Patients who develop acute pulmonary complications after evacuation of a molar pregnancy appear to be at extremely high risk for persistent trophoblastic disease. The paper details the management and follow-up of this patient.
在一名患有妊娠滋养细胞疾病的患者中，通过静脉注射前列腺素F2α诱导孕中期流产。子宫排空后，患者出现了严重的急性呼吸窘迫综合征（ARDS）。该综合征被认为是由滋养细胞栓子、出血性休克、妊娠渗透压失衡或弥散性血管内凝血引起的。此外，还必须讨论前列腺素的间接副作用。葡萄胎妊娠排空后出现急性肺部并发症的患者似乎发生持续性滋养细胞疾病的风险极高。本文详细介绍了该患者的治疗及随访情况。
