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[顶叶皮层电刺激背景下食物性条件反射的辨别性抑制和消退性抑制]

[Discriminative and extinctive inhibition of alimentary conditioned reflexes against a background of electric stimulation of the parietal cortex].

作者信息

Danilova L K

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1981 Sep-Oct;31(5):933-40.

PMID:7314913
Abstract

Changes in differentiation and extinction inhibition of alimentary secretory conditioned reflexes during electrical stimulation of parietal cortical zones with a weak subthreshold current of 1 to 100 imp/s frequency were studied in dogs with electrodes implanted in the cerebral cortex. It was found that stimulation of these associative cortical areas results in disinhibition of differentiation inhibition. The depth of the disturbance depends on the frequency of the stimulating current: with high frequency stimulation, the effects of disinhibition are much more pronounced. Extinction of the conditioned alimentary reflex to an acoustic stimulus during stimulation is also impeded and is accompanied by motor alimentary excitation, particularly when the parietal cortex is stimulated by the high-frequency current.

摘要

在植入大脑皮层电极的犬中,研究了用频率为1至100次/秒的微弱阈下电流对顶叶皮层区进行电刺激时,食物分泌性条件反射的分化和消退抑制的变化。发现刺激这些联合皮层区域会导致分化抑制的去抑制。干扰的深度取决于刺激电流的频率:高频刺激时,去抑制的效果更为明显。刺激期间对声刺激的条件食物反射的消退也受到阻碍,并伴有食物性运动兴奋,特别是当顶叶皮层受到高频电流刺激时。

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