隐形眼镜引起的角膜内皮细胞短暂变化。

Contact lens induced transient changes in corneal endothelium.

作者信息

Antti V, Jukka M, Jukka S, Reijo A, Esko J

出版信息

Acta Ophthalmol (Copenh). 1981 Aug;59(4):552-9. doi: 10.1111/j.1755-3768.1981.tb08342.x.

DOI:10.1111/j.1755-3768.1981.tb08342.x

Abstract

The effect of soft contact lens (SCL) wear on corneal epithelium was studied with a noncontact specular microscope in 21 unadapted young volunteers. In 4 cases the specular reflection remained intact. In 6 cases the specular reflection was abnormally pronounced in the cell periphery and less pronounced in the central cell area. Nine of 21 eyes presented also nonreflecting areas or blebs. In 2 individuals these changes were extensive. The changes appeared 4 to 10 min after the contact lens (CL) insertion and reached a maximum after 15 to 40 min. The endothelial mosaic returned to normal about 30 min after removal of the CL. The endothelial bleb reaction and the role of atmospheric oxygen flux to the endothelium is discussed.

摘要

使用非接触式角膜内皮显微镜对21名未适应的年轻志愿者佩戴软性隐形眼镜（SCL）后角膜上皮的影响进行了研究。4例患者的镜面反射保持完整。6例患者的镜面反射在细胞周边异常明显，而在中央细胞区域则不太明显。21只眼中有9只眼还出现了无反射区或小泡。在2名个体中，这些变化广泛。这些变化在插入隐形眼镜（CL）后4至10分钟出现，并在15至40分钟后达到最大值。摘除CL后约30分钟，内皮镶嵌恢复正常。讨论了内皮小泡反应以及大气氧通量对内皮的作用。