Anderlik P, Wessely M, Szeri I, Bános Z, Rápolthy I U, Budai J
Acta Microbiol Acad Sci Hung. 1981;28(4):359-65.
Germfree and conventional mice responded similarly to pertussis vaccine treatment. In both groups, lymphocytosis and splenomegaly developed in a similar proportion. The formalin stress reaction of germfree and conventional mice with hypertrophic lymphoid organs induced by pertussis vaccine differed from that of untreated mice: the treated germfree and conventional mice showed a acute increase of lymphocytosis without an significant change in splenomegaly.
无菌小鼠和普通小鼠对百日咳疫苗治疗的反应相似。在两组中,淋巴细胞增多和脾肿大的发生率相似。由百日咳疫苗诱导产生肥厚性淋巴器官的无菌小鼠和普通小鼠的福尔马林应激反应与未治疗小鼠不同:经治疗的无菌小鼠和普通小鼠淋巴细胞增多急性增加,而脾肿大无显著变化。