Hennessey R, Reinhart J H, McGuckin M B
Am J Med Technol. 1981 Nov;47(11):909-11.
A forty year old man was admitted with suspected subacute bacterial endocarditis. Neisseria mucosa was isolated in pure culture. Initial antibiotic therapy included penicillin and gentamicin. After onset of allergic symptoms, penicillin was discontinued and vancomycin therapy instituted. Gentamicin therapy was discontinued after the serum creatinine began to rise. Minimum inhibitory concentration indicated that N mucosa was resistant to vancomycin. After allergy testing proved negative, intravenous penicillin therapy was reinstituted and continued until discharge, at which time the patient was to continue on oral penicillin for six months.
一名40岁男性因疑似亚急性细菌性心内膜炎入院。分离出了纯培养的黏液奈瑟菌。初始抗生素治疗包括青霉素和庆大霉素。出现过敏症状后，停用青霉素并开始使用万古霉素治疗。血清肌酐开始升高后停用庆大霉素治疗。最低抑菌浓度表明黏液奈瑟菌对万古霉素耐药。过敏试验证明为阴性后，重新开始静脉注射青霉素治疗并持续至出院，出院时患者继续口服青霉素六个月。
