Person J R, Rogers R S
Arch Dermatol. 1981 Nov;117(11):701-4.
Of nine patients with ashy dermatosis, eight were women; most were young adults when the dermatosis began. The incidences of atopy (five patients) and thyroid disease (three patients) were striking. Although some of the patients were clinically atypical, histologic study in all cases showed basal cell vacuolation, Civatte bodies, pigmentary incontinence, and a mild perivascular lymphohistiocytic infiltrate. Direct immunofluorescence microscopy, performed in four cases, showed igM cytoid bodies. We hypothesize that the postinflammatory hyperpigmentation in ashy dermatosis and, perhaps, in other dermatoses may occur on the basis of basal cell apoptosis.
在9例灰皮病患者中，8例为女性；大多数患者在皮肤病开始时为年轻成年人。特应性疾病（5例）和甲状腺疾病（3例）的发病率引人注目。尽管有些患者临床表现不典型，但所有病例的组织学研究均显示基底细胞空泡化、西瓦特小体、色素失禁和轻度血管周围淋巴细胞-组织细胞浸润。4例患者进行了直接免疫荧光显微镜检查，显示有IgM细胞样小体。我们推测，灰皮病以及或许其他皮肤病中的炎症后色素沉着可能基于基底细胞凋亡而发生。
