Mendelowitz D S, Kimmins S, Evans W E
Arch Surg. 1981 Dec;116(12):1587-91. doi: 10.1001/archsurg.1981.01380240067010.
Of 358 patients referred for evaluation of cerebral vascular insufficiency over a ten-year period (January 1971 to April 1981), 32 were isolated who had experienced hemispheric transient ischemic attacks (TIAs), and lacking other identifiable abnormality were found angiographically to be free of suspicious extracranial occlusive or ulcerated lesions. These patients were studied retrospectively to evaluate their prognosis in terms of cerebral infarction and recurrent neurologic symptoms. In a mean follow-up of 16 months, ranging from three months to four years, no patient suffered a cerebral infarction. Six had further symptoms; however three were due to other abnormalities found subsequently. Three patients continued to be symptomatic; however, only one patient had recurrent hemispheric symptoms, the others being global and vague in description. Severe hypertension was associated with an increased risk of further attacks. The data indicate that the prognosis for patients with normal angiograms and hemispheric TIAs, lacking other identifiable abnormality, is good.
在1971年1月至1981年4月的十年间,358例因脑血管供血不足接受评估的患者中,有32例孤立性半球短暂性脑缺血发作(TIA)患者,血管造影未发现其他可识别的异常,也未发现可疑的颅外闭塞性或溃疡性病变。对这些患者进行回顾性研究,以评估他们发生脑梗死和复发性神经症状的预后。平均随访16个月(范围从3个月到4年),没有患者发生脑梗死。6例出现了进一步的症状;然而,3例是由于随后发现的其他异常。3例患者持续有症状;然而,只有1例患者有复发性半球症状,其他患者的症状描述为全身性且模糊不清。严重高血压与进一步发作的风险增加有关。数据表明,血管造影正常且有半球TIA、无其他可识别异常的患者预后良好。