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[猫大脑皮层树突的年龄相关变化(电子显微镜研究)]

[Age-related changes in the dendrites in the cat cerebral cortex (an electron microscopic study)].

作者信息

Iontov A S, Shefer V F

出版信息

Arkh Anat Gistol Embriol. 1981 Oct;81(10):11-6.

PMID:7316783
Abstract

Various zones of the acoustic cortex (A1, A3, A4, Ep after Voolsey) have been serially studied in two cats 12-14 years of age at electron microscopic level. Various forms of age changes have been revealed in their dendrites. The most often occurring form of the changes is the dendrites with lipofuscin granules in them. The dendrites with neuroplasm filled with numerous, sometimes aggregating electron opaque formations of various size and contour make the second form. Appearance of separate electron opaque round myelin-like bodies scattered in the dendritic neuroplasm precede the appearance of the third form. There is a various degree of disturbances in the interneuronal contacts. They depend on age alterations in the dendrites which are the most widespread postsynaptic components in the cerebral cortex. The importance to perform age selection of animals for an experimental morphological interneuronal connection investigations is stressed.

摘要

在电子显微镜水平上,对两只12 - 14岁猫的听觉皮层的不同区域(A1、A3、A4、Voolsey之后的Ep区)进行了系列研究。在它们的树突中发现了各种形式的年龄变化。最常见的变化形式是含有脂褐素颗粒的树突。充满大量有时聚集的各种大小和轮廓的电子不透明结构的神经浆树突构成了第二种形式。散布在树突神经浆中的单独的电子不透明圆形髓磷脂样小体的出现先于第三种形式的出现。神经元间的接触存在不同程度的紊乱。它们取决于树突中的年龄变化,而树突是大脑皮层中分布最广泛的突触后成分。强调了在进行实验性形态学神经元间连接研究时对动物进行年龄选择的重要性。

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