Hautmann R, Hering F J, Lutzeyer W
J Urol. 1978 Dec;120(6):712-5. doi: 10.1016/s0022-5347(17)57338-3.
Absorptive hypercalciuria was treated in 27 patients with cellulose phosphate. In all patients urinary calcium decreased and stone formation virtually ceased. The most striking side effect was an excessive hyperoxaluria, necessitating withdrawal of the drug in 8 patients. Succinate decreased the hyperoxaluria in 14 of 19 patients. All patients had mild hypercalciuria and hypermagnesiuria. This study was done to determine the therapeutic value and the side effects in the treatment of absorptive hypercalciuria with sodium cellulose phosphate and of hyperoxaluria with succinate.
对27例吸收性高钙尿症患者使用磷酸纤维素进行治疗。所有患者的尿钙均下降，结石形成几乎停止。最显著的副作用是草酸尿过多，8例患者因此停药。19例患者中有14例使用琥珀酸盐后草酸尿减少。所有患者均有轻度高钙尿症和高镁尿症。本研究旨在确定用磷酸纤维素钠治疗吸收性高钙尿症以及用琥珀酸盐治疗高草酸尿症的治疗价值和副作用。
