Fukuda S, Matsuoka O
Jikken Dobutsu. 1981 Oct;30(4):497-501. doi: 10.1538/expanim1978.30.4_497.
The maturation process of the secondary ossification centers of the extremities was radiographically investigated in the Japanese white rabbit of both sexes aged 1 day to 78 weeks. The ossification centers appeared at 1 day of age in the proximal and distal epiphyses of humerus, the head of femur, the distal epiphysis of femur and the proximal epiphysis of tibia, at 1 week of age in the supraglenoid tubercle of scapula, the proximal and distal epiphyses of radius, the proximal and distal epiphyses of ulna, the greater trochanter of femur, the distal epiphysis of tibia and the distal epiphysis of fibula, and at 2 weeks of age in the proximal epiphysis of fibula. The ossification centers developed rapidly from the time of appearance to 8 weeks of age, and gradually thereafter until 32 weeks of age. By 78 weeks of age, the complete fusion with the diaphysis was observed in the supraglenoid tubercle of scapula, the proximal and distal epiphyses of humerus, the head and distal epiphysis of femur. Incomplete fusion, leaving an epiphyseal line, was found in the proximal and distal epiphyses of radius, ulna, tibia and fibula, respectively.
对1日龄至78周龄的日本白兔两性四肢二级骨化中心的成熟过程进行了影像学研究。骨化中心在1日龄时出现在肱骨近端和远端骨骺、股骨头、股骨远端骨骺和胫骨近端骨骺；在1周龄时出现在肩胛骨盂上结节、桡骨近端和远端骨骺、尺骨近端和远端骨骺、股骨大转子、胫骨远端骨骺和腓骨远端骨骺；在2周龄时出现在腓骨近端骨骺。骨化中心从出现到8周龄迅速发育，此后逐渐发育直至32周龄。到78周龄时，在肩胛骨盂上结节、肱骨近端和远端骨骺、股骨头和股骨远端骨骺观察到与骨干完全融合。在桡骨、尺骨、胫骨和腓骨的近端和远端骨骺分别发现不完全融合，留有骨骺线。
