Morita N, Ito S, Isaka N, Murata Y, Kawanami C, Konishi T, Hamada M, Nakano T, Takezawa H
J Cardiogr. 1981 Sep;11(3):765-77.
The echocardiographic study was performed in 13 cases with infective endocarditis including one case with annular subvalvular left ventricular (LV) aneurysm. The echocardiographic findings were compared with clinical as well as anatomical findings obtained by surgery or autopsy. The valvular vegetations were visualized echocardiographically in 6 cases (46%); 2 cases in aortic valve (AV), 2 in mitral valve (MV) and 2 in both valves. In 3 out of 4 cases with AV vegetation, the abnormal echo was seen in the LV outflow tract. Two out of these 3 cases indicated "flail aortic leaflet" with early closure of the MV, and immediate aortic valve replacement was performed. Unfortunately, one died 4 weeks after operation. The echocardiographic findings showed good correlation with anatomical findings in 4 cases with valve replacement. Out of 4 cases with MV vegetation, one developed the progressive growth with subsequent rupture of the chordae tendinae to the anterior mitral leaflet, which paralleled to the clinical deterioration. In another one case, the echocardiographic size of vegetation in the MV reduced significantly shortly after the episode of cerebral embolism. In a case of annular subvalvular LV aneurysm possibly due to infective endocarditis, echo free space was visualized in the interventricular septum, coinciding well with postmortem anatomical findings. It seemed to be reasonable to indicate surgical repair in cases with evident vegetation and considerable destruction of AV, in which congestive heart failure inevitably develops and the prognosis is poor.
对13例感染性心内膜炎患者进行了超声心动图研究,其中1例伴有瓣环下左心室(LV)动脉瘤。将超声心动图检查结果与手术或尸检获得的临床及解剖学结果进行了比较。超声心动图显示6例(46%)有瓣膜赘生物;主动脉瓣(AV)2例,二尖瓣(MV)2例,双瓣膜2例。在4例有AV赘生物的患者中,3例在LV流出道可见异常回声。这3例中有2例显示“连枷样主动脉瓣叶”伴MV提前关闭,并立即进行了主动脉瓣置换。不幸的是,1例术后4周死亡。4例瓣膜置换患者的超声心动图结果与解剖学结果显示出良好的相关性。在4例有MV赘生物的患者中,1例赘生物逐渐增大,随后腱索断裂至二尖瓣前叶,这与临床病情恶化情况相符。在另一例中,脑栓塞发作后不久,MV赘生物的超声心动图大小显著减小。在1例可能因感染性心内膜炎导致的瓣环下LV动脉瘤病例中,室间隔可见无回声区,与尸检解剖结果吻合良好。对于有明显赘生物且AV有相当程度破坏、不可避免会发展为充血性心力衰竭且预后不良的病例,建议进行手术修复似乎是合理的。