Christensen G
Nord Vet Med. 1981 Apr-May;33(4-5):236-49.
Within a Danish practice area a serological examination was made of 268 breeding animals in 25 conventional sow herds with a view to screening for herd infection with haemophilus pleuropneumoniae. Average size of the herds was 76 year-sows including pregnant gilts (8--200). In 23 herds produced weaners were fed for slaughtering. The frequency of chronic pleuritis in slaughtered baconers in these herds was related to the frequency of seropositive sows in the herds. Three SPF-herds were included in the investigation, a SPF baconer herd reinfected with H. pleuropneumoniae, a SPF baconer herd reinfected with Mycoplasma suipneumoniae and a SPF breeding herd infected with Haemophilus parasuis. Complement fixation antibodies against Haemophilus pleuropneumoniae were found in breeding animals in 22 out of the 25 conventional sow herds. The average incidence of seropositive breeding animals in infected herds was 62% (7%--100%), highest in the largest herds. Likewise the highest serotitres were found in the largest herds, as an expression of strong infection pressure in large herds. The highest titre values were found in boars and young sows. The frequency of seronegative sows was the highest among the oldest sows. The registered frequency of chronic pleuritis among baconers from the examined herds was found increasing along with higher frequency of seropositive sows in the herds. On the basis of these observations and on the basis of a comparison of chronic pleuritis frequency among baconers in six herds (two with high frequency of seropositive breeding animals, one with moderate frequency of seropositive breeding animals, and 3 SPF-herds, one of which had been reinfected with Haemophilus pleuropneumoniae, one reinfected with Mycoplasma suipneumoniae and one that had experienced an acute outbreak of Glässer's Syndrome) it is concluded that haemophilus pleuropneumoniae is the absolutely most important cause of chronic pleuritis in baconers. A pronounced seasonal variation was found in the monthly pleuritis frequency among baconers in herds strongly infected with Haemophilus pleuropneumoniae, the minumum frequency being in January-February, and the maximum frequency in July-October. It is supposed that the observed variation in frequency of chronic pleuritis is caused by changes in the environmental climate. High frequency of chronic pleuritis is caused by changes in the environmental climate. High frequency is found in the summer in slaughtered baconers, which have been clinically affected by pleuropneumonia as piglets and weaners under inferior climatic conditions during the colder season of the year.
在丹麦一个特定区域内，对25个传统母猪群中的268头种畜进行了血清学检测，旨在筛查胸膜肺炎放线杆菌的群体感染情况。这些猪群的平均规模为76头经产母猪，包括怀孕的后备母猪（8 - 200头）。在23个猪群中，断奶仔猪被饲养用于屠宰。这些猪群中屠宰的育肥猪慢性胸膜炎的发生率与猪群中血清阳性母猪的发生率相关。调查中纳入了3个无特定病原体（SPF）猪群，一个感染了胸膜肺炎放线杆菌的SPF育肥猪群，一个感染了猪肺炎支原体的SPF育肥猪群，以及一个感染了副猪嗜血杆菌的SPF繁殖猪群。在25个传统母猪群中的22个猪群的种畜中发现了针对胸膜肺炎放线杆菌的补体结合抗体。感染猪群中血清阳性种畜的平均发生率为62%（7% - 100%），在最大的猪群中发生率最高。同样，最高血清滴度也出现在最大的猪群中，这表明大猪群中有很强的感染压力。最高滴度值出现在公猪和年轻母猪中。血清阴性母猪的比例在最老的母猪中最高。在所检查猪群的育肥猪中，慢性胸膜炎的登记发生率随着猪群中血清阳性母猪比例的增加而增加。基于这些观察结果，以及对六个猪群（两个血清阳性种畜比例高的猪群、一个血清阳性种畜比例中等的猪群和3个SPF猪群，其中一个感染了胸膜肺炎放线杆菌，一个感染了猪肺炎支原体，一个经历了格拉泽氏综合征急性暴发）育肥猪慢性胸膜炎发生率的比较，得出结论：胸膜肺炎放线杆菌是育肥猪慢性胸膜炎绝对最重要的病因。在感染胸膜肺炎放线杆菌严重的猪群中，育肥猪每月胸膜炎发生率存在明显的季节性变化，最低发生率在1月至2月，最高发生率在7月至10月。据推测，观察到的慢性胸膜炎发生率的变化是由环境气候的变化引起的。慢性胸膜炎的高发生率是由环境气候的变化引起的。在夏季屠宰的育肥猪中发现高发生率，这些育肥猪在一年中较冷季节气候条件较差时作为仔猪和断奶仔猪曾受到胸膜肺炎的临床影响。
