Bazelly B, Marchand M, de Riberolles C, Neveux J Y
Nouv Presse Med. 1981 Dec 5;10(44):3629-30.
The authors report a case of recurrent cerebral embolism in a 43-year-old patient with a familial form of Rendu-Osler-Weber disease and review their experience of 19 cases of pulmonary arteriovenous fistula. Neurological complications were rare but considerably aggravated the disease. They were due to a significant right/left shunt but remained unpredictable, being unrelated to peripheral arterial saturation. The pathophysiological mechanisms and therapeutic possibilities are discussed.
作者报告了一例43岁患有家族性遗传性出血性毛细血管扩张症(Rendu-Osler-Weber病)的复发性脑栓塞病例,并回顾了他们对19例肺动静脉瘘的治疗经验。神经并发症虽罕见,但会使病情显著加重。这些并发症是由明显的右向左分流引起的,但仍然无法预测,与外周动脉血氧饱和度无关。本文讨论了其病理生理机制和治疗可能性。