Suzuki T, Nakagawa K, Kanno Y, Ichinoe S, Toyozaki N, Ito T
Radioisotopes. 1981 Jul;30(7):366-71.
The urinary aldosterone (ALD) was measured by aldosterone RIA kit and the following results were obtained. (1) We have known that ten percent solution of bovine serum albumin (BSA) instead of free serum LAD is used as the diluent of the urine in aldosterone RIA kit. (2) The upper limits of free ALD, HCl-ALD and beta-glucuronidase ALD in the urine diluted with 10% BSA were 1.6, 9.0 and 9.5 micrograms/dl respectively. (3) The values of urinary conjugated HCl-ALD and beta-glucuronidase ALD were approximately 3.5 times and 4 times as much as that of free ALD respectively. (4) A good correlation was obtained among the results of three methods (HCl-ALD, beta-glucuronidase ALD and free ALD). (5) No difference was found in the values of the urinary ALD in the healthy subjects and the patients with essential hypertension, kidney diseases and acute liver diseases.
采用醛固酮放射免疫分析试剂盒测定尿醛固酮(ALD),结果如下:(1)我们已经知道,在醛固酮放射免疫分析试剂盒中,用10%牛血清白蛋白(BSA)溶液代替游离血清LAD作为尿液稀释剂。(2)用10% BSA稀释的尿液中游离ALD、HCl-ALD和β-葡萄糖醛酸酶ALD的上限分别为1.6、9.0和9.5微克/分升。(3)尿结合HCl-ALD和β-葡萄糖醛酸酶ALD的值分别约为游离ALD的3.5倍和4倍。(4)三种方法(HCl-ALD、β-葡萄糖醛酸酶ALD和游离ALD)的结果之间具有良好的相关性。(5)健康受试者与原发性高血压、肾脏疾病和急性肝病患者的尿ALD值无差异。