Weiss L
Med Biol. 1978 Dec;56(6):398-402.
When Walker-256 cancer cells are injected into the portal veins of rats bearing Walker-256 tumours in their livers, the retention of the injected cancer cells by the tumours is considerably less than in the surrounding liver. After applying defined general criteria for "homing" phenomena to the data, it is concluded that compared with the liver, they demonstrate "antihoming". The observations are explained in terms of a deficient arrest process within the tumours.
将Walker-256癌细胞注入肝脏已存在Walker-256肿瘤的大鼠门静脉后，肿瘤对注入癌细胞的滞留能力远低于周围肝脏。在将“归巢”现象的明确通用标准应用于这些数据后，得出结论：与肝脏相比，肿瘤表现出“抗归巢”。这些观察结果可以用肿瘤内阻滞过程不足来解释。
