Anderberg B, Gillquist J, Larsson L, Lundström B
Acta Chir Scand. 1981;147(2):109-13.
Seventy-three patients were operated on for confirmed hyperparathyroidism. Identification of all glands was done by 1/3 biopsies for histopathologic examination on frozen section during the operation. In cases of adenoma only, the adenoma was removed except for the biopsies. In cases of hyperplasia, subtotal resection was made, leaving between a half-gland and a whole gland. The frequency of complications was analysed. Temporary hypocalcemia occurred in a similar frequency in both adenoma and hyperplasia groups. Permanent hypocalcemia was present in only one patient. At follow-up 3-5 years after operation, 98.6% of the patients were normocalcemic. Ionized and total serum calcium were normalized 3 months after operation and remained so for the rest of the follow-up period. Serum phosphate, serum magnesium and serum parathormone also remained normal. Thus identification of parathyroid glands with biopsies or subtotal parathyroidectomy in cases with hyperplasia did not increase the risk of postoperative complications.
73例患者因确诊甲状旁腺功能亢进接受手术治疗。术中通过对所有腺体进行1/3活检，以在冰冻切片上进行组织病理学检查来识别腺体。仅在腺瘤病例中，除活检部分外，将腺瘤切除。在增生病例中，进行次全切除术，保留半个腺体至一个完整腺体。分析并发症的发生率。腺瘤组和增生组中暂时性低钙血症的发生率相似。仅1例患者出现永久性低钙血症。术后3至5年随访时，98.6%的患者血钙正常。术后3个月时，血清离子钙和总钙恢复正常，并在剩余随访期内保持正常。血清磷、血清镁和血清甲状旁腺激素也保持正常。因此，在增生病例中通过活检识别甲状旁腺或进行甲状旁腺次全切除术不会增加术后并发症的风险。
