Vester-Andersen T, Christiansen C, Hansen A, Sørensen M, Meisler C
Acta Anaesthesiol Scand. 1981 Apr;25(2):81-4. doi: 10.1111/j.1399-6576.1981.tb01612.x.
In a prospective clinical study including 100 patients, the consequences of using the interscalene approach to block the brachial plexus were investigated according to the area of analgesia, complications, and blood concentrations of local anesthetics. Sufficient analgesia of the shoulder and the upper part of the arm was obtained in 98-99% of the cases, whilst the area of analgesia in the forearm and the hand was more variable. In two groups, with 10 patients in each group, the blood concentration was measured during the first 50 min after injection in the neurovascular sheath by either the interscalene or the axillary approach. The peak values were at the same level in the two groups, but there was a much more rapid rise in concentration in the interscalene group. No toxic reactions were seen. The complications were in accordance with those reported in other publications.
在一项纳入100例患者的前瞻性临床研究中，根据镇痛区域、并发症以及局部麻醉药的血药浓度，对采用肌间沟入路阻滞臂丛神经的后果进行了研究。98%至99%的病例获得了肩部和上臂上部充分的镇痛效果，而前臂和手部的镇痛区域则更具变异性。在两组中，每组10例患者，通过肌间沟或腋窝入路在神经血管鞘内注射后最初50分钟内测量血药浓度。两组的峰值处于同一水平，但肌间沟组的浓度上升要快得多。未观察到毒性反应。并发症与其他出版物报道的一致。
