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[大鼠的蛋白质供应与转氨酶及琥珀酸脱氢酶活性]

[Protein supply of rats and transaminase and succinate dehydrogenase activity].

作者信息

Grassmann E, Tschierschwitz A, Roth F X, Kirchgessner M

出版信息

Arch Tierernahr. 1981 Oct;31(10):661-6. doi: 10.1080/17450398109426873.

DOI:10.1080/17450398109426873
PMID:7325795
Abstract

The influence of an isocaloric diet containing 13 and 20% of crude protein on the activities of GOT, GPT and succinic dehydrogenase in rat livers was determined and compared to the growth as well as to the body composition of the animals. The weights of the animals were significantly increased, feed efficiency and consumption of metabolizable energy per gram of body increase were much better with higher protein supply. It may be concluded that protein retention was better while fat retention was nearly unaffected. The activities of the liver enzymes increased with the protein content of the diet, especially GOT 1,8 times and succinic dehydrogenase 3 times as compared to the respective values of the lower protein group. It is discussed that the activity of succinic dehydrogenase represents a suitable criterion for the evaluation of a changed metabolism, especially when protein supply is marginal.

摘要

测定了含13%和20%粗蛋白的等热量饮食对大鼠肝脏中谷草转氨酶(GOT)、谷丙转氨酶(GPT)和琥珀酸脱氢酶活性的影响,并将其与动物的生长情况及身体组成进行了比较。动物体重显著增加,蛋白质供应较高时,饲料效率和每克体重增加所消耗的代谢能量更佳。可以得出结论,蛋白质潴留情况较好,而脂肪潴留几乎未受影响。肝脏酶的活性随饮食中蛋白质含量的增加而升高,与低蛋白组的相应值相比,谷草转氨酶尤其升高了1.8倍,琥珀酸脱氢酶升高了3倍。文中讨论了琥珀酸脱氢酶的活性是评估代谢变化的一个合适标准,尤其是在蛋白质供应处于临界水平时。

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