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[在连续传代的乳腺癌细胞中检测D型肿瘤病毒]

[Detection of oncornavirus type D in continuous breast cancer cells].

作者信息

Abenova U A, Il'in K V, Tsareva A A, Priory E, Peterson C

出版信息

Vopr Virusol. 1977 Sep-Oct(5):609-12.

PMID:73258
Abstract

An oncornavirus immunologically similar to oncornaviruses type D previously isolated from human continuous cells was detected in continuous cells of mammary cancer (SH3). The culture produces structures having densities of 1.18--1.19 and 1.22 g/ml which contain high molecular RNA (68S) and reverse-transcriptase activity. The similarity of this virus with other oncornaviruses was also demonstrated in molecular hybridization experiments.

摘要

在乳腺癌连续细胞系(SH3)中检测到一种与先前从人连续细胞系中分离出的D型肿瘤病毒在免疫学上相似的肿瘤病毒。该培养物产生密度为1.18--1.19和1.22克/毫升的结构,其中含有高分子量RNA(68S)和逆转录酶活性。在分子杂交实验中也证明了这种病毒与其他肿瘤病毒的相似性。

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