Zaĭtseva K K, Simonenkova V A, Komar Iu A, Kudrin V N
Arkh Patol. 1981;43(12):40-7.
Early morphological changes in the lungs in multiple mechanical damages to the body characterized by lack of hemathorax and fractures of the tubular bones were studied histologically and electron microscopically in 140 random-bred experimental rats. It was shown that initial changes in the lungs consisted of fatty embolism and damage to the pulmonary capillaries endothelium followed by edema of interalveolar septae and circulatory disorders, massive infiltration of interalveolar septae with neutrophilic leukocytes, extensive atelectases. The experimental results supplement and specify the data on the pathogenesis of acute respiratory insufficiency in severe mechanical injuries (polytraumas).
对140只随机繁殖的实验大鼠进行了组织学和电子显微镜研究，这些大鼠身体多处受到机械损伤，其特征为无血胸和管状骨骨折。结果表明，肺部的初始变化包括脂肪栓塞和肺毛细血管内皮损伤，随后出现肺泡间隔水肿和循环障碍、肺泡间隔大量中性粒细胞浸润、广泛肺不张。实验结果补充并明确了严重机械损伤（多发伤）中急性呼吸功能不全发病机制的数据。
