贝斯勒姆品系：大鼠高低饲养活动的遗传选择

The Bethlem lines: genetic selection for high and low rearing activity in rats.

作者信息

Sanders D C

出版信息

Behav Genet. 1981 Sep;11(5):491-503. doi: 10.1007/BF01070005.

Abstract

A foundation population derived from nine different rat strains was subjected to genetic selection for high and low rearing activity. A rapid response to selection was demonstrated, the two selected lines showing virtually no overlap in scores after 10 generations. Heritability estimates were assessed from parent-offspring regressions in the unselected control line and from comparisons of the achieved response with the selection pressure applied in the selected lines. Overall, the heritability of rearing activity in the rat was assessed to be about 0.25. In addition, a major gene effect was revealed, albinism being associated with low rearing activity scores.

摘要

从九个不同大鼠品系中获得一个基础种群，对其进行高饲养活动和低饲养活动的遗传选择。结果表明对选择有快速反应，经过10代后，两个选择品系在得分上几乎没有重叠。通过未选择的对照品系中的亲子回归以及将获得的反应与选择品系中施加的选择压力进行比较来评估遗传力估计值。总体而言，大鼠饲养活动的遗传力估计约为0.25。此外，还揭示了一个主要基因效应，白化与低饲养活动得分相关。