Danguy A, Leclercq G, Pasteels J L, Heuson J C
Bull Assoc Anat (Nancy). 1981 Mar;65(188):67-75.
Cytochemical steroids binding activity of human mammary cancer cells is demonstrated in cryostat frozen sections using hydrophilic fluorescent steroid hormone ligands. The cytochemical results indicate that mammary carcinomas are composed of heterogeneous populations of positive and negative cancer cells in varying proportions. A comparison with biochemical data was made. There exists no correlation between the results obtained with the histochemical and the biochemical techniques. The specificity of this new tool of investigation is discussed.
利用亲水性荧光甾体激素配体，在低温恒温器冷冻切片中证实了人乳腺癌细胞的细胞化学甾体结合活性。细胞化学结果表明，乳腺癌由比例各异的阳性和阴性癌细胞异质群体组成。并与生化数据进行了比较。组织化学和生化技术所得结果之间不存在相关性。讨论了这种新研究工具的特异性。
