Holden J E, Ip W R
Med Phys. 1978 Nov-Dec;5(6):485-90. doi: 10.1118/1.594458.
Computed tomography is sensitive to changes in the imaged distribution during acquisition of the projection data. Previous investigations have emphasized discrete or discontinuous changes in the imaged object. Recent advances have motivated our investigation of object time-dependence characterized by a continuous function in time at each point. Formal mathematical and computer simulation approaches have been developed, and are presented along with simple examples of their applications. Further applications in three distinct ongoing studies are outlined.
计算机断层扫描对投影数据采集过程中成像分布的变化很敏感。先前的研究强调了成像对象中的离散或不连续变化。最近的进展促使我们对对象的时间依赖性进行研究，其特征是在每个点上随时间呈连续函数变化。已经开发了形式化的数学和计算机模拟方法，并结合简单的应用示例进行了介绍。还概述了在三项不同的正在进行的研究中的进一步应用。
