Gratz E S, Pollack M A, Zimmerman R D
Int J Pediatr Otorhinolaryngol. 1981 Dec;3(4):335-41. doi: 10.1016/0165-5876(81)90058-6.
Congenital facial palsy and ipsilateral deafness were found in two children of unrelated insulin-requiring diabetics. Multidirectional tomography showed hypoplasia of the internal auditory canal in each case but the cochlea, vestibule and semicircular canals were radiologically normal. The malformation in these patients must have been determined before 23 weeks of gestational age when ossification of the inner ear is complete. The association of this malformation and maternal diabetes is unlikely to be coincidental.
在两名无亲缘关系的胰岛素依赖型糖尿病患者的子女中发现了先天性面瘫和同侧耳聋。多向断层扫描显示,每例患者的内耳道均发育不全,但耳蜗、前庭和半规管在放射学上正常。这些患者的畸形肯定是在妊娠23周内耳骨化完成之前就已确定。这种畸形与母亲糖尿病之间的关联不太可能是巧合。