皮下注射肝素治疗引起的高转氨酶血症。
Hypertransaminasemia with subcutaneous heparin therapy.
作者信息
Shilo S, Abraham A S, Breuer R, Sonnenblick M
出版信息
Isr J Med Sci. 1981 Dec;17(12):1133-5.
An elevation of serum aspartate aminotransferase (GOT) and alanine aminotransferase (GPT) may be produced in patients treated with i.v. full-dose HEPARIN. We studied the influence of low-dose s.c. HEPARIN (5,000 IU X 2) in 34 patients with acute myocardial infarction (AMI) and in 7 with cerebrovascular accidents or calf thrombophlebitis. Twelve patients (all males) with AMI showed a secondary elevation of GOT and GPT at about the sixth or seventh day after the commencement of therapy that persisted throughout the period of treatment. Four patients (two males and two females) with cerebrovascular accidents or thrombophlebitis showed similar increases of GOT and GPT.
静脉注射全剂量肝素治疗的患者可能会出现血清天冬氨酸转氨酶（GOT）和丙氨酸转氨酶（GPT）升高。我们研究了低剂量皮下注射肝素（5000国际单位×2）对34例急性心肌梗死（AMI）患者以及7例脑血管意外或小腿血栓性静脉炎患者的影响。12例AMI患者（均为男性）在治疗开始后约第六或第七天出现GOT和GPT继发性升高，并在整个治疗期间持续存在。4例脑血管意外或血栓性静脉炎患者（2例男性和2例女性）也出现了类似的GOT和GPT升高。
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