David T J
J Med Genet. 1981 Oct;18(5):344-9. doi: 10.1136/jmg.18.5.344.
The palmar dermatoglyphs of 800 patients with anatomically proven congenital heart disease were compared with prints from 1000 controls. A review of the previous studies revealed major technical deficiencies, and the present study failed to confirm most of the previously reported positive findings. An overall increase in the incidence of hypothenar patterns was found, probably explaining the previous suggestion of increased atd angle in congenital heart disease. A large number of statistical comparisons inevitably produced a few 'significant' results, most of which were inconsistent in various ways. Two percent of cases were found to have rare epidermal ridge malformation, ridge dissociation. The nature of the relationship between this and congenital heart disease is obscure. Claims that there are diagnostically useful dermatoglyphic changes in congenital heart disease can be disregarded.
对800例经解剖证实患有先天性心脏病的患者的掌部皮纹与1000例对照者的指纹进行了比较。对先前研究的回顾揭示了主要的技术缺陷,并且本研究未能证实大多数先前报道的阳性结果。发现小鱼际纹型的发生率总体增加,这可能解释了先前关于先天性心脏病中atd角增大的观点。大量的统计比较不可避免地产生了一些“显著”结果,其中大多数在各种方面并不一致。发现2%的病例有罕见的表皮嵴畸形,即嵴分离。其与先天性心脏病之间关系的性质尚不清楚。关于先天性心脏病存在诊断上有用的皮纹变化的说法可以不予理会。