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坦桑尼亚宫颈癌高剂量后装远距离放射治疗:早期结果

High dose remote afterloading radiotherapy for cervix carcinoma in Tanzania: early results.

作者信息

Alexander G A, Henschke U K

出版信息

J Natl Med Assoc. 1981 Dec;73(12):1141-7.

Abstract

From February 1977 through January 1979, 206 patients with histologically confirmed cervix carcinoma were treated with high dose rate afterloading irradiation at the Muhimbili Medical Center of the University of Dar es Salaam, Tanzania. Tribal and regional patterns of disease conform to geographical distributions of referring hospitals. The age at presentation, namely, at over 40 years, is similar to that reported elsewhere from East Africa. Parity among patients ranged from 0 to 14 pregnancies. Vaginal bleeding was the most common symptom in 69 percent of patients. Squamous cell carcinoma was noted in 96 percent of cases. Seventy-six percent of patients had early stage disease. Good initial responses to treatment were recorded in 57 percent of patients. Follow-up of cervical cancer patients is poor. Fifty-six (27 percent) patients were followed 1 to 17 months after treatment. Due to poor follow-up, no definite conclusions are reached regarding late radiation reactions and patient survival. The role or radiotherapy in reducing morbidity, however, is of importance.

摘要

1977年2月至1979年1月期间,坦桑尼亚达累斯萨拉姆大学穆希姆比利医疗中心对206例经组织学确诊的宫颈癌患者进行了高剂量率后装放疗。疾病的部落和区域模式与转诊医院的地理分布相符。就诊时的年龄,即40岁以上,与东非其他地方报告的年龄相似。患者的产次从0次到14次妊娠不等。69%的患者中,阴道出血是最常见的症状。96%的病例为鳞状细胞癌。76%的患者处于疾病早期。57%的患者治疗初期反应良好。宫颈癌患者的随访情况不佳。56例(27%)患者在治疗后1至17个月接受了随访。由于随访不佳,关于晚期放射反应和患者生存情况未得出明确结论。然而,放疗在降低发病率方面的作用很重要。

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