Chisholm J C
J Natl Med Assoc. 1981 Dec;73(12):1151-4.
A case of hypergastrinemia, diarrhea, and relentless hypokalemia occurring in a middleaged, mildly hypertensive female is described. The presence of a gastrinoma was suggested by the additional findings of an inordinate degree of hypokalemia for the amount of thiazide used for the treatment of her hypertension; failure of her hypokalemia to correct itself with adequate doses of oral potassium that had previously corrected this problem; and amelioration of her symptoms and hypokalemia when she was treated with short-term oral potassium chloride and longterm cimetidine.
本文描述了一例发生在中年轻度高血压女性患者身上的高胃泌素血症、腹泻及持续性低钾血症病例。治疗高血压所用噻嗪类药物剂量与低钾血症程度极不相称；以往口服足量钾能纠正低钾血症，但此次未能纠正；短期口服氯化钾及长期服用西咪替丁治疗后症状及低钾血症改善，这些额外发现提示存在胃泌素瘤。
