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缺血性心脏病中的血液甲状腺激素(与冠状动脉造影数据、心绞痛严重程度及血脂水平的比较)

[Blood thyroid hormones in ischemic heart disease (a comparison with coronary angiographic data, severity of stenocardia and blood lipid level)].

作者信息

Sidorenko B A, Begliarov M I, Titov V N, Masenko V P, Parkhimovich R M

出版信息

Kardiologiia. 1981 Dec;21(12):96-101.

PMID:7329025
Abstract

The blood concentration of the thyroid hormones, thyroid stimulating hormone and lipids were estimated in 67 patients with ischemic heart disease (IHD), 12 patients with hypothyroidism (H) and 19 normal controls. H was diagnosed in 9% of the patients with IHD. There were similar changes of the blood lipid concentrations in the patients with IHD (without H) and the patients with H (without IHD): increased level of the total cholesterol, triglycerides, cholesterol of the low and very low density lipoproteins. The blood level of cholesterol of high density lipoproteins (C-HDL) was significally higher in the patients with H than in the patients with IHD. There was correlation of the level of thyroxine in the blood and clinical severity of angina pectoris among the euthyroid patients with IHD having the same degree of coronary atherosclerosis.

摘要

对67例缺血性心脏病(IHD)患者、12例甲状腺功能减退症(H)患者和19名正常对照者的甲状腺激素、促甲状腺激素和血脂的血浓度进行了评估。在IHD患者中,9%被诊断为H。IHD患者(无H)和H患者(无IHD)的血脂浓度有相似变化:总胆固醇、甘油三酯、低密度和极低密度脂蛋白胆固醇水平升高。H患者的高密度脂蛋白胆固醇(C-HDL)血水平显著高于IHD患者。在具有相同程度冠状动脉粥样硬化的甲状腺功能正常的IHD患者中,血甲状腺素水平与心绞痛的临床严重程度存在相关性。

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