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公羊松果体切除对促黄体生成素、睾酮、催乳素和皮质醇分泌谱的影响。

Effects of pinealectomy of rams on secretory profiles of luteinizing hormone, testosterone, prolactin and cortisol.

作者信息

Barrell G K, Lapwood K R

出版信息

Neuroendocrinology. 1978;27(5-6):216-27. doi: 10.1159/000122814.

DOI:10.1159/000122814
PMID:732953
Abstract

In a study of pineal gland influences on hormone secretory profiles, blood samples were collected at 20 min intervals for 26 h from 4 pinealectomized and 4 sham-operated rams which were subjected to a 14.5 h daily photoperiod. Plasma levels of luteinizing hormone (LH) and testosterone (T) underwent rapid pulsatile fluctuations in all rams. Pinealectomized rams produced more LH than the sham-operated rams and a similar trend was recorded for plasma T data, since T secretion closely followed that of LH. A nocturnal elevation of plasma prolactin (Prl) levels displayed by sham-operated rams was substantially abolished by pinealectomy. Also a rise in cortisol secretion during the morning hours recorded from 3 of the sham-operated rams was absent in 2 of the pinealectomized rams. The possible significance of the pineal gland in the regulation of secretion of these hormones is discussed.

摘要

在一项关于松果体对激素分泌谱影响的研究中,对4只松果体切除的公羊和4只假手术的公羊,在每天14.5小时的光照周期下,每隔20分钟采集一次血样,共采集26小时。所有公羊的血浆促黄体生成素(LH)和睾酮(T)水平都经历了快速的脉冲式波动。松果体切除的公羊产生的LH比假手术的公羊更多,血浆T数据也记录到了类似的趋势,因为T的分泌紧密跟随LH的分泌。假手术公羊夜间血浆催乳素(Prl)水平的升高在松果体切除后基本消失。同样,3只假手术公羊在早晨记录到的皮质醇分泌增加在2只松果体切除的公羊中并未出现。本文讨论了松果体在这些激素分泌调节中的可能意义。

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