Holness R O, Hoffman H J, Mancer K, Armstrong D
Neurosurgery. 1978 Mar-Apr;2(2):143-7. doi: 10.1227/00006123-197803000-00013.
A very rare combination of two rare entities is reported. The patient had anterior sacral and intrasacral meningoceles, which were repaired at age 3 years, and 7 years later he presented with hypopituitarism due to a suprasellar teratocarcinoma. There has been no evidence of tumor recurrence in the 2.5 years since subtotal excision and radiotherapy (patient was last seen in 1977). Two aspects of the case are reviewed: the unusual nature of the spinal defect and the implications of its association with an intracranial tumor of developmental origin.
报告了两种罕见病症的极为罕见的组合。该患者患有骶前和骶内脑脊膜膨出，在3岁时进行了修复，7年后因鞍上畸胎癌出现垂体功能减退。自次全切除和放疗后2.5年（患者最后一次就诊于1977年），尚无肿瘤复发的证据。本文回顾了该病例的两个方面：脊柱缺损的不寻常性质及其与发育起源的颅内肿瘤相关联的影响。
