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儿童血液透析期间透析液中的甲状腺激素浓度

Thyroid hormone concentrations in dialysate during hemodialysis in children.

作者信息

Waters W, Bulla M, Buschsieweke U, Kutzim H

出版信息

Nuklearmedizin. 1981 Dec;20(6):272-3.

PMID:7329808
Abstract

Thyroxine (T4) concentration in dialysate in the course of hemodialysis was determined in 15 children. Concentrations were measured by a modified radioimmunoassay. During hemodialysis there was a slight increase in T4 concentration. At the end of hemodialysis T4 concentration was about 50% higher than soon after the onset of hemodialysis. The loss of T4 into dialysate during hemodialysis was 19.2 microgram; the loss of T3 was less than 75 ng. The amount of the daily loss of thyroid hormones into dialysate was found to be in the range of normal urinary excretion. The lowering of serum thyroid hormone concentrations in children on hemodialysis cannot be explained by the loss of hormones into dialysate.

摘要

对15名儿童在血液透析过程中透析液中的甲状腺素(T4)浓度进行了测定。浓度通过改良放射免疫分析法进行测量。血液透析期间,T4浓度略有升高。血液透析结束时,T4浓度比透析开始后不久高约50%。血液透析期间T4进入透析液的量为19.2微克;T3的丢失量小于75纳克。发现甲状腺激素每日进入透析液的丢失量在正常尿液排泄范围内。血液透析患儿血清甲状腺激素浓度降低不能用激素进入透析液的丢失来解释。

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