Walker J F, O'Neil S, Campbell E, Browne O, Doyle G, Carmody M, O'Dwyer W F
Postgrad Med J. 1981 Sep;57(671):592-6. doi: 10.1136/pgmj.57.671.592.
Nephrotic syndrome has been observed in association with different types of neoplasia. This appears to be the first report of the occurrence of the nephrotic syndrome due to membrano proliferative glomerulonephritis in association with carcinoma of the oesophagus. Although proteinuria was present before excision of the tumour, the nephrotic phase occurred subsequently. Eventually it disappeared leaving the patient with a clear urine and biochemical and histological improvement of the renal lesion (including immunofluorescent and electronmicroscopy studies). Possible mechanisms responsible for the nephrotic syndrome in this case are discussed.
肾病综合征已被观察到与不同类型的肿瘤相关。这似乎是首例关于食管癌细胞膜增生性肾小球肾炎导致肾病综合征的报道。尽管在肿瘤切除前就已存在蛋白尿，但肾病阶段随后才出现。最终蛋白尿消失，患者尿液清澈，肾脏病变在生化和组织学上得到改善（包括免疫荧光和电子显微镜研究）。本文讨论了该病例中导致肾病综合征的可能机制。
