Leclerc M, Brillouet C, Luquet G, Agogue P, Binaghi R A
Scand J Immunol. 1981 Sep;14(3):281-4. doi: 10.1111/j.1365-3083.1981.tb00565.x.
The in vitro effects of pokeweed mitogen (PWM) on axial organ (AO) cells of the echinoderm starfish Asteria rubens have been studied. PWM stimulates 3H-thymidine incorporation by the whole population of AO cells (index of stimulation 4-5). On the basis of surface adherence to nylon wool the AO cell population can be fractionated into adherent and non-adherent subpopulations. PWM strongly stimulates the non-adherent cells (index 14) but not the adherent cells (index 1.2-1.8). Specific soluble mediators obtained from stimulated non-adherent cells were able to stimulate the whole AO cell population but not the fractionated adherent or non-adherent cells.
对商陆丝裂原（PWM）作用于棘皮动物红海星轴器官（AO）细胞的体外效应进行了研究。PWM可刺激整个AO细胞群体对³H-胸腺嘧啶核苷的掺入（刺激指数为4 - 5）。基于在尼龙纤维上的表面黏附特性，AO细胞群体可分为黏附亚群和非黏附亚群。PWM强烈刺激非黏附细胞（指数为14），但不刺激黏附细胞（指数为1.2 - 1.8）。从受刺激的非黏附细胞中获得的特异性可溶性介质能够刺激整个AO细胞群体，但不能刺激分离出的黏附或非黏附细胞。
