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职业人群妊娠结局研究中的设计考量

Design considerations in pregnancy outcome studies of occupational populations.

作者信息

Selevan S G

出版信息

Scand J Work Environ Health. 1981;7 Suppl 4:76-82.

PMID:7330634
Abstract

Increased attention has been focused on the relationship between adverse pregnancy outcomes and occupational exposures to parents of both sexes. However, the characteristics and dynamics of working populations impose limitations on potential study populations. These limitations result from the combined effects of workforce size, exposure, age distribution, and marital status, which limit the number of pregnancies available for study. The smaller populations available typically result in retrospective studies covering extended time periods. Potential data sources for these studies include interview data, medical records, vital statistics data, and insurance records. All sources may have biased ascertainment of certain pregnancy outcomes such as early fetal loss due to errors in recall in interview data, legal requirements for recording vital statistics data, and differences in medical care patterns.

摘要

人们越来越关注不良妊娠结局与父母双方职业暴露之间的关系。然而,劳动人口的特征和动态对潜在研究人群构成了限制。这些限制是由劳动力规模、暴露情况、年龄分布和婚姻状况的综合影响造成的,它们限制了可供研究的妊娠数量。通常可获得的较小人群导致了覆盖较长时间段的回顾性研究。这些研究的潜在数据来源包括访谈数据、医疗记录、人口动态统计数据和保险记录。所有来源在确定某些妊娠结局时可能存在偏差,例如由于访谈数据中的回忆错误、人口动态统计数据记录的法律要求以及医疗护理模式的差异导致的早期胎儿丢失。

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Design considerations in pregnancy outcome studies of occupational populations.职业人群妊娠结局研究中的设计考量
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引用本文的文献

1
Birthweight of term infants and maternal occupation in a prospective cohort of pregnant women. The ALSPAC Study Team.孕妇前瞻性队列中足月儿出生体重与母亲职业。阿冯纵向研究父母与儿童队列研究团队。
Occup Environ Med. 1998 Jan;55(1):18-23. doi: 10.1136/oem.55.1.18.
2
Epidemiological studies in monitoring reproductive effects.监测生殖影响的流行病学研究。
Environ Health Perspect. 1993 Oct;101 Suppl 3(Suppl 3):279-83. doi: 10.1289/ehp.93101s3279.
3
Interagency regulatory liaison group workshop on reproductive toxicity risk assessment.跨部门监管联络小组生殖毒性风险评估研讨会
Environ Health Perspect. 1986 Apr;66:193-221. doi: 10.1289/ehp.8666193.
4
Choice of control population in studies of adverse reproductive effects of occupational exposures and its effect on risk estimates.职业暴露对生殖的不良影响研究中对照人群的选择及其对风险估计的影响。
Br J Ind Med. 1987 Apr;44(4):244-9. doi: 10.1136/oem.44.4.244.
5
Healthy worker effect and pregnancy: role of adverse obstetric history and social characteristics.健康工人效应与妊娠:不良产科史和社会特征的作用。
J Epidemiol Community Health. 1987 Dec;41(4):312-20. doi: 10.1136/jech.41.4.312.