Mims J L, Shields J A
Ophthalmology. 1978 Sep;85(9):929-43. doi: 10.1016/s0161-6420(78)35597-4.
The fundus photographs and fluorescein angiograms of 255 consecutive cases of choroidal nevi were reviewed. Sixty-one cases (24%) were selected as suspicious on the basis of strict preestablished criteria including greatest single diameter, elevation, degree of disruption of the retinal pigment epithelium, and presence of subretinal fluid. Fifty of these 61 had adequate four-year follow-up. The remaining 194 cases, labeled as nonsuspicious, were usually small, relatively flat, slate-grey nevi which failed to meet the criteria for being suspicious. Of the 50 suspicious choroidal nevi followed four years, five (10%) showed photographic evidence of growth 4 to 30 months after the last examination. In contrast, none of the 194 nonsuspicious cases demonstrated growth. On the basis of these results, recommendations are made for the management of suspicious choroidal nevi.
回顾了连续255例脉络膜痣患者的眼底照片和荧光素血管造影。根据预先严格设定的标准，包括最大单一直径、隆起度、视网膜色素上皮破坏程度和视网膜下液的存在，选出61例（24%）可疑病例。这61例中的50例有足够的四年随访资料。其余194例被标记为非可疑病例，通常为小的、相对扁平的、石板灰色的痣，不符合可疑标准。在随访四年的50例可疑脉络膜痣中，5例（10%）在最后一次检查后4至30个月有照片证据显示有生长。相比之下，194例非可疑病例均未显示生长。基于这些结果，对可疑脉络膜痣的处理提出了建议。
