Ramelet A A, Delacrétaz J
Dermatologica. 1981;163(5):361-9.
38 biopsies of perioral dermatitis have been examined. The following has consistently been observed: follicular hyperkeratosis; vasodilatation and oedema (sometimes very pronounced) of the papillary dermis; perivascular and parafollicular infiltrates consisting predominantly of lymphocytes, histiocytes and polymorphonuclear leucocytes. Occasionally, there have been epithelioid or giant cells, sarcoid-like infiltrates or vasculitis of the leucoclastic type. Demodex folliculorum was observed in only two sections and the follicles that contained them were not inflamed. This histological picture is very similar to that of acne rosacea.
对38例口周皮炎活检标本进行了检查。一直观察到以下情况：毛囊角化过度；乳头层真皮血管扩张和水肿（有时非常明显）；血管周围和毛囊周围浸润，主要由淋巴细胞、组织细胞和多形核白细胞组成。偶尔会出现上皮样或巨细胞、类肉瘤样浸润或白细胞破碎型血管炎。仅在两个切片中观察到毛囊蠕形螨，且含有它们的毛囊未发炎。这种组织学表现与酒渣鼻非常相似。
