Hicks J M, Iosefsohn M, Silber T J, Boeckx R L
J Adolesc Health Care. 1981 Sep;2(1):45-8. doi: 10.1016/s0197-0070(81)80085-x.
In order to study the sensitivity and efficiency of five pregnancy tests, we evaluated four types of urine tests in 162 adolescent girls in whom pregnancy was suspected; a serum test was performed in 46 of them. We found that (1) an increase in sensitivity occurred at the expense of specificity, (2) the quantitation of the beta-subunit of human chorionic gonadotropin in serum proved to be the most reliable test for pregnancy, and (3) the latex agglutination inhibition tube test (Placentex) was the most accurate of the four types of urine tests evaluated. We concluded that for adolescents, the serum pregnancy test is the preferred test, but when it is not available, the urine latex agglutination inhibition tube test offers the most reliable alternative.
为研究五种妊娠试验的敏感性和效率，我们对162名疑似怀孕的青春期女孩进行了四种尿液试验评估；其中46人还进行了血清试验。我们发现：（1）敏感性的提高是以特异性为代价的；（2）血清中人绒毛膜促性腺激素β亚基的定量检测被证明是最可靠的妊娠试验；（3）在评估的四种尿液试验中，乳胶凝集抑制试管试验（Placentex）最为准确。我们得出结论，对于青少年而言，血清妊娠试验是首选，但在无法进行血清试验时，尿液乳胶凝集抑制试管试验是最可靠的替代方法。
