Kasantikul V, Brown W J, Cahan L D
J Neurol Neurosurg Psychiatry. 1981 Dec;44(12):1110-5. doi: 10.1136/jnnp.44.12.1110.
Two examples of intracerebral neurilemmoma occurred in the absence of von Recklinghausen's disease. The first case was unique because the patient was clinically asymptomatic, and the second case was unusual with a combination of oligodendroglioma and neurilemmoma in the same mass. The latter lesion arising in persons without stigmata of neurofibromatosis has not been described. The nature of nerve sheath neoplasms in both instances has been verified by electron-microscopy. Clinical features of this rare neoplasm differ from those of acoustic or other cranial nerve tumour, particularly in relation to age and sex. Intracerebral neurilemmoma has been found most often in the first two decades of life and more often in males. Seizures and paresis, although non-specific are common signs and symptoms. Probable histogenesis of this neoplasm from perivascular elements in brain has been suggested.
两例脑内神经鞘瘤发生于无冯雷克林霍增氏病(神经纤维瘤病)的患者。第一例很独特,因为患者临床上无症状;第二例不寻常,同一肿块内合并有少突胶质细胞瘤和神经鞘瘤。后者发生于无神经纤维瘤病体征的患者,此前未见报道。两例神经鞘瘤的性质均经电子显微镜证实。这种罕见肿瘤的临床特征与听神经瘤或其他颅神经肿瘤不同,尤其是在年龄和性别方面。脑内神经鞘瘤最常发生于生命的前二十年,男性更为多见。癫痫发作和轻瘫虽然不具特异性,但却是常见的体征和症状。有人提出这种肿瘤可能起源于脑内血管周围成分。