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[关于通过考虑低感染强度的实验性肝片吸虫感染对绵羊性能和代谢过程进行改良的研究]

[Studies on the modification of performance and metabolic processes in sheep through experimental Fasciola hepatica infections considering low infestation intensity].

作者信息

Buchwalder R, Daetz H H, Hiepe T, Schmidt H U

出版信息

Angew Parasitol. 1977 Jun;18(2):65-9.

PMID:73356
Abstract

Low experimental infections with Fasciola hepatica (8...17 flukes per animal) in sheep, 6...12 months old, caused less gain weight over a period of 22 weeks. Changes in the number of erythrocytes and in the Hb-concentration were not found. In contrast to the controls the infected sheep showed strong fluctuations in the number of lymphocytes. 3 weeks post infect. a significant eosinophilia was observed, which continued until the end of the investigation. With the beginning of the fourth week post infect. the values of serum albumin were lower, the values of gamma-globulin higher than those of the controls, but there was no statistical significance. The bromosulphalein-test for liver function was negative.

摘要

对6至12月龄的绵羊进行低剂量肝片吸虫实验性感染(每只动物感染8至17条吸虫),在22周的时间里体重增加较少。未发现红细胞数量和血红蛋白浓度有变化。与对照组相比,受感染绵羊的淋巴细胞数量出现强烈波动。感染后3周,观察到明显的嗜酸性粒细胞增多,这种情况一直持续到调查结束。感染后第四周开始,血清白蛋白值较低,γ球蛋白值高于对照组,但无统计学意义。肝功能的溴磺酞钠试验为阴性。

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