Martin B W, Terry M K, Bridges C H, Bailey E M
Vet Hum Toxicol. 1981 Dec;23(6):416-7.
Three Shetland ponies were given a single oral dose of ground Cassia occidentalis seeds in aqueous suspension. The clinical signs observed resembled those seen in naturally occurring and experimental cases in cattle. The syndrome was characterized by an afebrile course, incoordination, recumbency and death. Elevations of blood alkaline phosphatase, CPK, LDH, and SGOT were observed. Although muscle lesions were not seen grossly, microscopic lesions included segmental necrosis of skeletal muscle fibers. The findings were regarded as sufficiently characteristic of C. occidentalis poisoning to be useful in differential diagnosis. When Cassia poisoning is suspected, access of the affected horses to the plant should be demonstrated.
给三头设得兰矮种马口服了一次磨碎的望江南种子的水悬浮液。观察到的临床症状与牛自然发生和实验病例中所见的症状相似。该综合征的特征是无热病程、共济失调、卧地不起和死亡。观察到血液碱性磷酸酶、肌酸磷酸激酶、乳酸脱氢酶和谷草转氨酶升高。虽然大体上未见到肌肉病变，但显微镜下病变包括骨骼肌纤维的节段性坏死。这些发现被认为对望江南中毒具有足够的特征性，有助于鉴别诊断。当怀疑望江南中毒时，应证明受影响的马匹接触过该植物。
