Schmauder H P, Maier W, Gröger D
Z Allg Mikrobiol. 1981;21(9):689-92. doi: 10.1002/jobm.3630210908.
The influence of amitrole (3-amino-1,2,4-triazole) on growth, alkaloid formation and on some aromatic as well as ergoline pathway specific enzymes were studied in Claviceps strain, SD 58. In a phosphate-rich medium the addition of amitrole can partially reverse the alkaloid-depressing effect of phosphate. Using a typical fermentation medium amitrole reduces the activities of ergoline specific enzymes but increases drastically tryptophan synthase activity and to a lesser extent transaminase of aromatic amino acids.
研究了杀草强(3-氨基-1,2,4-三唑)对麦角菌菌株SD 58的生长、生物碱形成以及一些芳香族和麦角灵途径特异性酶的影响。在富含磷酸盐的培养基中,添加杀草强可部分逆转磷酸盐对生物碱的抑制作用。使用典型的发酵培养基时,杀草强会降低麦角灵特异性酶的活性,但会大幅提高色氨酸合成酶的活性,并在较小程度上提高芳香族氨基酸转氨酶的活性。