Marchionni M, Penna C, Fallani M G, Innocenti Degli A I, Scuderi A, Scarselli G
Eur J Gynaecol Oncol. 1981;2(2):51-6.
The Authors have observed by colposcopy and cytology, 401 patients under the age of 20 and have compared the results obtained with those of a similar control group with ages ranging from 20 to 25. They observed the incidence of normal cervix and of other colposcopic reports. From the comparison between the colposcopic and cytologic data emerged that the cytopathologic diagnosis does not put the cervical alterations of inferior level than dysplasia in evidence, in a large number cases as colposcopy does. There is a very close relation between the incidence of pathologic cervical lesions and sexual activity. Correlation between cervical pathology and use of hormonal contraceptives and presence of cervico-vaginal phlogosis, was not possible in this type of survey. The Authors therefore propose a new type of mass screening, which should substitute the actual one, that is substantially based on cytology and on early diagnosis rather than prevention.
作者通过阴道镜检查和细胞学检查观察了401名20岁以下的患者，并将所得结果与年龄在20至25岁之间的类似对照组的结果进行了比较。他们观察了正常宫颈的发生率以及其他阴道镜检查报告。通过阴道镜检查和细胞学数据之间的比较发现，在大量病例中，细胞病理学诊断不像阴道镜检查那样能显示出低于发育异常水平的宫颈改变。宫颈病理病变的发生率与性活动之间存在非常密切的关系。在这类调查中，无法确定宫颈病理与激素避孕药的使用以及宫颈阴道炎症之间的相关性。因此，作者提出了一种新型的大规模筛查，它应该取代目前主要基于细胞学和早期诊断而非预防的筛查方式。
