布美他尼治疗肝硬化难治性腹水：与呋塞米的比较。
Bumetanide in refractory ascites of cirrhosis of the liver: a comparison with furosemide.
作者信息
Iber F L, Baum R A
出版信息
J Clin Pharmacol. 1981 Nov-Dec;21(11):697-700. doi: 10.1002/j.1552-4604.1981.tb05686.x.
Abstract
Bumetanide and furosemide were compared in the treatment of resistant ascites in patients with liver disease of alcoholic origin. In a prospective randomized trial, no significant difference was found in the ability of these two agents to promote natriuresis or diuresis. The duration of action was 12 hours for bumetanide and 6 hours for furosemide, but this difference was of no clinical significance.
摘要
比较了布美他尼和呋塞米在治疗酒精性肝病患者顽固性腹水中的效果。在一项前瞻性随机试验中，未发现这两种药物在促进利钠或利尿能力上有显著差异。布美他尼的作用持续时间为12小时，呋塞米为6小时，但这种差异无临床意义。
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